AMOTL1 antibody (AA 441-490)

Catalog No. ABIN1534635

This Rabbit Polyclonal antibody specifically detects AMOTL1 in ELISA, IHC and IF. It exhibits reactivity toward Human and Mouse.It has been mentioned in 1 publication

Quick Overview for AMOTL1 antibody (AA 441-490) (ABIN1534635)

Target: AMOTL1 (Angiomotin Like 1 (AMOTL1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AMOTL1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-AMOTL1 Antibody

Binding Specificity: AA 441-490

Purpose: Angiomotin-L1 Antibody

Specificity: Angiomotin-L1 Polyclonal Antibody detects endogenous levels of Angiomotin-L1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human AMOTL1. AA range:441-490

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

References for anti-AMOTL1 antibody (ABIN1534635)

Nakajima, Nakamura, Shigeeda, Tomoyasu, Deguchi, Tanita, Yamauchi: "The role of tumor necrosis factor-α and interferon-γ in regulating angiomotin-like protein 1 expression in lung microvascular endothelial cells." in: Allergology international : official journal of the Japanese Society of Allergology, Vol. 62, Issue 3, pp. 309-22, (2014) (PubMed).

Target Details for AMOTL1

Target: AMOTL1 (Angiomotin Like 1 (AMOTL1))

Alternative Name: AMOTL1

Background:

Synonyms: AMOTL1, Angiomotin-like protein 1

Background: The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],

Gene Name: AMOTL1

Protein Name: Angiomotin-like protein 1

Molecular Weight: 106 kDa

Gene ID: 154810

UniProt: Q8IY63