BUD31 antibody (AA 5-54)

Catalog No. ABIN1535588

Cited in 1 publication. The Rabbit Polyclonal anti-BUD31 antibody (ABIN1535588) specifically detects BUD31 in WB, ELISA, IHC and IF. The antibody is reactive with Human and Rat samples.

Quick Overview for BUD31 antibody (AA 5-54) (ABIN1535588)

Target: BUD31 (BUD31 Homolog (BUD31))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BUD31 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-BUD31 Antibody

Binding Specificity: AA 5-54

Purpose: EDG-2 Antibody

Specificity: EDG-2 Polyclonal Antibody detects endogenous levels of EDG-2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human EDG2. AA range:5-54

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

References for anti-BUD31 antibody (ABIN1535588)

Kataoka, Ishibashi, Kumagai, Yanagida, Aikawa, Chiba, Kojima: "Expression and Function of LPA1 in Bladder Cancer." in: The Journal of urology, Vol. 194, Issue 1, pp. 238-44, (2015) (PubMed).

Target Details for BUD31

Target: BUD31 (BUD31 Homolog (BUD31))

Alternative Name: EDG2

Background:

Synonyms: LPAR1, EDG2, LPA1, Lysophosphatidic acid receptor 1, LPA receptor 1, LPA-1, Lysophosphatidic acid receptor Edg-2

Background: lysophosphatidic acid receptor 1(LPAR1) Homo sapiens The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Two transcript variants encoding the same protein have been identified for this gene [provided by RefSeq, Jul 2008],

Gene Name: LPAR1

Protein Name: Lysophosphatidic acid receptor 1

Molecular Weight: 41 kDa

Gene ID: 1902

OMIM: 602282

UniProt: Q92633