BIRC7 antibody (C-Term)

Catalog No. ABIN155074

This Rabbit Polyclonal antibody specifically detects BIRC7 in WB. It exhibits reactivity toward Human.

Quick Overview for BIRC7 antibody (C-Term) (ABIN155074)

Target: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BIRC7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BIRC7 Antibody

Binding Specificity: C-Term

Specificity: The antibody detects a band at ~33 kDa and a weaker band at 30 kDa, corresponding to Livin α and β.

Purification: Peptide affinity purified

Immunogen: Synthetic peptide surrounding amino acid near the C- terminus of the long form of human Livin

Application Details

Application Notes: Western Blot: 2-6 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Target Details for BIRC7

Target: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Alternative Name: BIRC7 / LIVIN

Background: Livin is a novel member in the IAP (inhibitor of apoptosis) protein family. Livin contains a single baculoviral IAP repeat (BIR) domain and a RING finger domain and has two isoforms termed Livin-α and Livin-β. Transfection of Livin protected cells from apoptosis induced by FADD, BAX, RIP, RIP3 and DR6. Livin directly react with several caspases including Caspase-3, -7, and -9, and it inhibits the activation of caspase-9 induced by Apaf-1, cytochrome c and ATP.Synonyms: Baculoviral IAP repeat-containing protein 7, KIAP, Kidney inhibitor of apoptosis protein, Livin, MLIAP, Melanoma inhibitor of apoptosis protein, RING finger protein 50, RNF50

Gene ID: 79444

NCBI Accession: NP_071444

UniProt: Q96CA5