PSPH antibody (AA 1-225)

Catalog No. ABIN165446

The Mouse Monoclonal anti-PSPH antibody is suitable to detect PSPH in samples from Human. It has been validated for WB, ELISA, ICC and IF.

Quick Overview for PSPH antibody (AA 1-225) (ABIN165446)

Target: PSPH (Phosphoserine Phosphatase (PSPH))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PSPH antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: 3G12

Product Details anti-PSPH Antibody

Binding Specificity: AA 1-225

Purpose: Human Phosphoserine phosphatase/PSPH antibody

Purification: Purified

Immunogen: Recombinant human PSP (1-225aa) purified from E. coli

Isotype: IgG1 kappa

Application Details

Application Notes: Recommended dilution 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for PSPH

Target: PSPH (Phosphoserine Phosphatase (PSPH))

Alternative Name: Phosphoserine phosphatase/PSPH

Background: Human phosphoserine phosphatase (HPSP), specific for D- and L- phosphoserine, has been identified in all human tissues. HPSP is a Mg (2+) -dependent phosphoserine phosphatase. The three dimensional structure of HPSP reveals the structural and functional role of the divalent cation in the active site of phosphatases. In particular, the complex structures reveal that the open-closed environmental change of the active site, generated by local rearrangement of the alpha-helical bundle domain, is important for the substrate recognition and hydrolysis.

NCBI Accession: NP_004568

Pathways: Warburg Effect