Folate Receptor 4 antibody

Catalog No. ABIN1713789

The Rabbit Polyclonal anti-Folate Receptor 4 antibody (ABIN1713789) specifically detects Folate Receptor 4 in WB, IF, IHC (fro) and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Folate Receptor 4 antibody (ABIN1713789)

Target: Folate Receptor 4 (FOLR4) (Folate Receptor 4 (Delta) (FOLR4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Folate Receptor 4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Folate Receptor 4 Antibody

Purpose: Folate Receptor 4 Polyclonal Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Folate Receptor 4

Isotype: IgG

Application Details

Application Notes: WB(1:500-2000), IHC-P(1:100-500), IHC-F(1:100-500), IF(1:100-500)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Folate Receptor 4

Target: Folate Receptor 4 (FOLR4) (Folate Receptor 4 (Delta) (FOLR4))

Alternative Name: Folate Receptor 4

Background:

Synonyms: Sperm-egg fusion protein Juno, Folate receptor 4, Folate receptor delta, FR-delta, FOLR4, JUNO

Background: Folate receptor 4 is a highly expressed cell surface marker of regulatory T cells. Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for gamete recognition and fertilization. The IZUMO1:FOLR4/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. This receptor does not bind folate.

Gene ID: 390243

UniProt: A6ND01