CD79a antibody (AA 202-216) (FITC)

Catalog No. ABIN181097

The Mouse Monoclonal anti-CD79a antibody is suitable to detect CD79a in samples from Human, Mouse, Rat, Cow, Pig, Monkey, Chicken, Rabbit, Horse, Guinea Pig and Dog. It has been validated for FACS.

Quick Overview for CD79a antibody (AA 202-216) (FITC) (ABIN181097)

Target: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Reactivity: Human, Mouse, Rat, Cow, Pig, Monkey, Chicken, Rabbit, Horse, Guinea Pig, Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD79a antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Clone: HM57

Product Details anti-CD79a Antibody (FITC)

Binding Specificity: AA 202-216

Specificity: This antibody recognises an epitope within the cytoplasmic domain of CD79a. Species: Human, Monkey, Pig, Horse, Bovine Guinea Pig, Rat, Mouse, Rabbit and Chicken. Others not tested.

Characteristics: Synonyms: IGA, MB1, B-Cell marker, B-cell antigen receptor complex-associated protein alpha-chain,MB-1 membrane glycoprotein, Surface IgM-associated protein, Membrane-boundimmunoglobulin-associated protein

Immunogen: Synthetic peptide corresponding to 202-216 amino acid sequence of Human mb-1. Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0 myeloma cellline. Genename: CD79a

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry: Use 10 µl of Neat-1/5 diluted antibody to label 1x10e6 cells in 100 µl(Membrane permeabilisation is required). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for CD79a

Target: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Alternative Name: CD79a

Background: CD79a, also known as mb-1, is a 45kD protein that is expressed by B lymphocytes duringdifferentiation from early pre-B cell stage through to plasma cells. The CD79a moleculeassociates with CD79b (B29) to form a heterodimer that is non-covalently linked to surfaceimmunoglobulin, forming the B-cell receptor (BCR) complex. The CD79a/CD79bheterodimers are also necessary for intracellular signalling following antigen-binding tosurface immunoglobulin.

UniProt: P11912

Pathways: BCR Signaling