MXD3 antibody (N-Term)

Catalog No. ABIN182330

There is 1 publication for this product available. The Rabbit Polyclonal anti-MXD3 antibody is suitable to detect MXD3 in samples from Human, Mouse, Rat, Dog, Cow, Horse, Rabbit and Pig. It has been validated for WB.

Quick Overview for MXD3 antibody (N-Term) (ABIN182330)

Target: MXD3 (MAX Dimerization Protein 3 (MXD3))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MXD3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MXD3 Antibody

Binding Specificity: N-Term

Purpose: MXD3 Antibody - N-terminal region

Sequence: PIHRRKKRPP QAPGAQDSGR SVHNELEKRR RAQLKRCLER LKQQMPLGAD

Predicted Reactivity: Cow: 93%, Dog: 86%, Horse: 93%, Human: 100%, Mouse: 85%, Pig: 86%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against MXD3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MXD3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP30089-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-MXD3 antibody (ABIN182330)

Suzuki, Yoshitomo-Nakagawa, Maruyama, Suyama, Sugano: "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library." in: Gene, Vol. 200, Issue 1-2, pp. 149-56, (1997) (PubMed).

Target Details for MXD3

Target: MXD3 (MAX Dimerization Protein 3 (MXD3))

Alternative Name: MXD3

Background:

Background Information: MXD3 contains 1 basic helix-loop-helix (bHLH) domain. It is a transcriptional repressor and binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.

Gene Name: MAX dimerization protein 3

Alternative Symbols: MYX, MAD3, BHLHC13

Protein Name: Max dimerization protein 3

Molecular Weight: 23kDa

Gene ID: 83463

NCBI Accession: NP_112590

UniProt: Q9BW11