SIRT3 antibody (C-Term)

Catalog No. ABIN182558

The Rabbit Polyclonal anti-SIRT3 antibody is suitable to detect SIRT3 in samples from Human, Mouse, Rat, Dog, Rabbit, Guinea Pig, Horse and Cow. It has been validated for WB.

Quick Overview for SIRT3 antibody (C-Term) (ABIN182558)

Target: SIRT3 (Sirtuin 3 (SIRT3))

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Guinea Pig, Horse, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIRT3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SIRT3 Antibody

Binding Specificity: C-Term

Sequence: VGPLAWHPRS RDVAQLGDVV HGVESLVELL GWTEEMRDLV QRETGKLDGP

Predicted Reactivity: Cow: 100%, Dog: 79%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against SIRT3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SIRT3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 399 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SIRT3

Target: SIRT3 (Sirtuin 3 (SIRT3))

Alternative Name: SIRT3

Background: SIRT3 is included in class I of the sirtuin family which is characterized by a sirtuin core domain. Human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.
Alias Symbols: SIR2L3
Protein Interaction Partner: SIRT5, SKP2, UBC, HSPD1, CMYA5, PGAP1, RIF1, NCAPD2, HERC2, TTF2, UQCRH, UGDH, HSP90B1, SNTB1, SBF1, HSPA9, HSPA5, HSPA4, HSPA1L, GRN, ATP5B, ATP5A1, SIRT4, tat, XRCC6, FOXO3, DNM1L, PEX5,
Protein Size: 399

Molecular Weight: 44 kDa

Gene ID: 23410

NCBI Accession: NM_012239, NP_036371

UniProt: Q9NTG7