HMG20A antibody (Middle Region)

Catalog No. ABIN182660

The Rabbit Polyclonal anti-HMG20A antibody has been validated for WB. It is suitable to detect HMG20A in samples from Human, Rat, Mouse, Dog, Rabbit, Horse, Cow and Guinea Pig.

Quick Overview for HMG20A antibody (Middle Region) (ABIN182660)

Target: HMG20A (High-Mobility Group 20A (HMG20A))

Reactivity: Human, Rat, Mouse, Dog, Rabbit, Horse, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMG20A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HMG20A Antibody

Binding Specificity: Middle Region

Sequence: RKTQDRQKGK SHRQDAARQA THDHEKETEV KERSVFDIPI FTEEFLNHSK

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HMG20A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HMG20A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 347 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HMG20A

Target: HMG20A (High-Mobility Group 20A (HMG20A))

Alternative Name: HMG20A

Background: HMG20A plays a role in neuronal differentiation as chromatin-associated protein. HMG20A acts as inhibitor of HMG20B. HMG20A overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. HMG20A involved in the recruitment of the histone methyltransferase MLL and consequent increased methylation of histone H3 lysine 4
Alias Symbols: FLJ10739, HMGX1, HMGXB1
Protein Interaction Partner: RSPH9, CFAP53, SYTL4, SCNM1, CCDC136, RPP30, HMG20A, PTH2R, KPNA2, HPCAL1, DTNB, FMNL1, ADD1, BRAP, UBC, HECW2, HTT, HDAC2, HDAC1, MTA3, KDM1A, SMAD4, ELAVL1, GTF2A1L, TESC, RBM7, CCNK, MAGOHB,
Protein Size: 347

Molecular Weight: 40 kDa

Gene ID: 10363

NCBI Accession: NM_018200, NP_060670

UniProt: Q9NP66