CDX4 antibody (C-Term)

Catalog No. ABIN182664

The Rabbit Polyclonal anti-CDX4 antibody (ABIN182664) specifically detects CDX4 in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Dog, Horse, Rabbit, Cow and Pig samples.

Quick Overview for CDX4 antibody (C-Term) (ABIN182664)

Target: CDX4 (Caudal Type Homeobox 4 (CDX4))

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDX4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CDX4 Antibody

Binding Specificity: C-Term

Purpose: CDX4 Antibody - C-terminal region

Sequence: KKISQFENSG GSVQSDSDSI SPGELPNTFF TTPSAVRGFQ PIEIQQVIVS

Predicted Reactivity: Cow: 92%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 100%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against CDX4. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CDX4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8096418

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDX4

Target: CDX4 (Caudal Type Homeobox 4 (CDX4))

Alternative Name: CDX4

Background:

Background Information: CDX are homeodomain transcription factors related to the Drosophila caudal gene. The vertebrate CDX have been implicated in the development of the posterior embryo. Several signaling molecules, notably retinoic acid (RA) and members of the Wnt (wingless) and fibroblast growth factor (FGF) families, are also implicated in patterning of the posterior vertebrate embryo. CDX family is the target of Wnt, RA and FGF signaling, suggesting that CDX factors act to convey the activity of these signaling molecules to Hox genes.

Gene Name: Caudal type homeobox 4

Protein Name: Homeobox protein CDX-4

Molecular Weight: 30kDa

Gene ID: 1046

NCBI Accession: NP_005184

UniProt: O14627