SOX11 antibody (N-Term)

Catalog No. ABIN182780

There is 1 publication for this product available. The Rabbit Polyclonal anti-SOX11 antibody is suitable to detect SOX11 in samples from Human, Rat, Mouse, Guinea Pig, Horse and Rabbit. It has been validated for WB.

Quick Overview for SOX11 antibody (N-Term) (ABIN182780)

Target: SOX11 (SRY (Sex Determining Region Y)-Box 11 (SOX11))

Reactivity: Human, Rat, Mouse, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX11 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SOX11 Antibody

Binding Specificity: N-Term

Purpose: SOX11 Antibody - N-terminal region

Sequence: MVQQAESLEA ESNLPREALD TEEGEFMACS PVALDESDPD WCKTASGHIK

Predicted Reactivity: Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against SOX11. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SOX11

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33327-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-SOX11 antibody (ABIN182780)

Li, Wang, Zheng, Zhao, Guo, Li, Bao, Zhang, Yang, Li: "Sox11 modulates neocortical development by regulating the proliferation and neuronal differentiation of cortical intermediate precursors." in: Acta biochimica et biophysica Sinica, Vol. 44, Issue 8, pp. 660-8, (2012) (PubMed).

Target Details for SOX11

Target: SOX11 (SRY (Sex Determining Region Y)-Box 11 (SOX11))

Alternative Name: SOX11

Background:

Background Information: This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis.

Gene Name: SRY (sex determining region Y)-box 11

Alternative Symbols: CSS9, MRD27

Protein Name: Transcription factor SOX-11

Molecular Weight: 47kDa

Gene ID: 6664

NCBI Accession: NP_003099

UniProt: P35716

Pathways: Tube Formation