Claudin 15 antibody (C-Term)

Catalog No. ABIN182857

This Rabbit Polyclonal antibody specifically detects Claudin 15 in WB. It exhibits reactivity toward Human and Cow.

Quick Overview for Claudin 15 antibody (C-Term) (ABIN182857)

Target: Claudin 15 (CLDN15)

Reactivity: Human, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 15 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Claudin 15 Antibody

Binding Specificity: C-Term

Purpose: CLDN15 Antibody - C-terminal region

Sequence: LCSACCCGSD EDPAASARRP YQAPVSVMPV ATSDQEGDSS FGKYGRNAYV

Predicted Reactivity: Cow: 77%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against CLDN15. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CLDN15

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8097498

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Claudin 15

Target: Claudin 15 (CLDN15)

Alternative Name: CLDN15

Background:

Background Information: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet.

Gene Name: Claudin 15

Protein Name: Claudin-15

Molecular Weight: 24kDa

Gene ID: 24146

NCBI Accession: NP_055158

UniProt: P56746

Pathways: Cell-Cell Junction Organization, Hepatitis C