Asialoglycoprotein Receptor 1 antibody (N-Term)

Catalog No. ABIN182885

The Rabbit Polyclonal anti-Asialoglycoprotein Receptor 1 antibody has been validated for WB. It is suitable to detect Asialoglycoprotein Receptor 1 in samples from Human, Mouse, Rat, Cow, Pig, Guinea Pig, Horse and Saccharomyces cerevisiae.

Quick Overview for Asialoglycoprotein Receptor 1 antibody (N-Term) (ABIN182885)

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Reactivity: Human, Mouse, Rat, Cow, Pig, Guinea Pig, Horse, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Asialoglycoprotein Receptor 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Asialoglycoprotein Receptor 1 Antibody

Binding Specificity: N-Term

Sequence: RKMKSLESQL EKQQKDLSED HSSLLLHVKQ FVSDLRSLSC QMAALQGNGS

Predicted Reactivity: Cow: 85%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 91%, Pig: 93%, Rat: 92%, Yeast: 75%

Characteristics: This is a rabbit polyclonal antibody against ASGR1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ASGR1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 291 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Asialoglycoprotein Receptor 1

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Alternative Name: ASGR1

Background: ASGR1 encodes for a cell surface receptor binds to galactose-terminated glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociates. Then the receptor is recycled back to the cell surface.
Alias Symbols: HL-1, ASGPR, ASGPR1, CLEC4H1
Protein Interaction Partner: CERS2, HIVEP1, SYVN1, VKORC1, FBXO6, EDEM1, HSPA5, CANX, APP, CLEC4G, NLK, RBBP6, HSP90B1, TG, HSP90AA1, DHFR, ASGR2, ITGA1,
Protein Size: 291

Molecular Weight: 33 kDa

Gene ID: 432

NCBI Accession: NM_001671, NP_001662

UniProt: Q6FGQ5

Pathways: Thyroid Hormone Synthesis