Kinesin Family Member 21A (KIF21A) (N-Term) antibody

Details for Product No. ABIN182908
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Antigen
Synonyms CG5300, DmCG5300, DmKlp31D, DmKlp31E, Dmel\\CG5300, KIF21A, kif21a, DKFZp469O1020, CFEOM1, FEOM1, FEOM3A, AI850764, mKIAA1708
Epitope
N-Term
(4), (1)
Reactivity
Cow (Bovine), Fruit Fly (Drosophila melanogaster), Human, Mouse (Murine), Rat (Rattus)
(4), (2)
Host
Rabbit
(6)
Clonality
Polyclonal
Application
Western Blotting (WB)
(6), (1), (1)
Pubmed 2 references available
Quantity 50 μg
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Immunogen Synthetic peptide directed towards the N terminal of human KIF21A
Sequence KEKRKKKSVA GKEDNTDTDQ EKKEEKGVSE RENNELEVEE SQEVSDHEDE
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Human : 100 %, Pig : 90 %, Rabbit : 90 %, Horse : 80 %, Mouse : 80 %, Guinea pig : 70 %, Rat : 70 %
Characteristics This is a rabbit polyclonal antibody against KIF21A. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name KIF21A (KIF21A Antibody Abstract)
Background KIF21A belongs to a family of plus end-directed kinesin motor proteins. Neurons use kinesin and dynein microtubule-dependent motor proteins to transport essential cellular components along axonal and dendritic microtubules.
Molecular Weight 186 kDa
Gene ID 55605
NCBI Accession NP_060111, NM_017641
UniProt Q7Z4S6
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 1661 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Product cited in: Shen, Meza-Carmen, Puxeddu et al.: "Interaction of brefeldin A-inhibited guanine nucleotide-exchange protein (BIG) 1 and kinesin motor protein KIF21A." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 48, pp. 18788-93, 2008 (PubMed).

Background publications Yamada, Chan, Andrews et al.: "Identification of KIF21A mutations as a rare cause of congenital fibrosis of the extraocular muscles type 3 (CFEOM3)." in: Investigative ophthalmology & visual science, Vol. 45, Issue 7, pp. 2218-23, 2004 (PubMed).

Validation Images
Catalog No. ABIN182908
289.00 $
Plus shipping costs $45.00
Quantity
Price
50 μg
289.00 $

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