TRIM68 antibody (C-Term)

Catalog No. ABIN183010

This Rabbit Polyclonal antibody specifically detects TRIM68 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Cow, Horse and Pig.

Quick Overview for TRIM68 antibody (C-Term) (ABIN183010)

Target: TRIM68 (Tripartite Motif Containing 68 (TRIM68))

Reactivity: Human, Mouse, Rat, Cow, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM68 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TRIM68 Antibody

Binding Specificity: C-Term

Purpose: TRIM68 Antibody - C-terminal region

Sequence: RLRKGNEYRA GTDEYPILSL PVPPRRVGIF VDYEAHDISF YNVTDCGSHI

Predicted Reactivity: Cow: 93%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against TRIM68. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TRIM68

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34460-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRIM68

Target: TRIM68 (Tripartite Motif Containing 68 (TRIM68))

Alternative Name: TRIM68

Background:

Background Information: The protein encoded by TRIM68 contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. TRIM68 is expressed in many cancer cell lines. Its expression in normal tissues, however, was found to be restricted to prostate. TRIM68 was also found to be differentially expressed in androgen-dependent versus androgen-independent prostate cancer cells.

Gene Name: Tripartite motif containing 68

Alternative Symbols: SS56, GC109, SS-56, RNF137

Protein Name: E3 ubiquitin-protein ligase TRIM68

Molecular Weight: 56kDa

Gene ID: 55128

NCBI Accession: NP_060543

UniProt: Q96PF7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling