NFKBIB / IKBB antibody

Antigen: NFKBIB / IKBB

Clonality: Polyclonal

Host: Rabbit

Reactivity: Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)

Application: Western Blotting (WB)

Catalog no.: ABIN183021

Additional Information

Description: Inhibition of NFkappa-B activity by the hepatitis C virus core protein might be related to its physical interaction with and interrupted nuclear localization of IKKbeta. Increased nuclear factor-kappaB (NF-kB) activity in the amnion during labor is associated with an increase in the expression of NF-kBp65 and of the NF-kB binding proteins IkBa, IkBb-1 and IkBb-2. IkappaBbeta may be a novel target for transcription factors of the HMG-box SRY/Sox family and imply a potential role for NF-kappaB/IkappaBbeta in spermatogenesis. Keywords: NFKBIB,nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta,ARP34505_T100,NP_002494,NM_002503,Q15653,HGNC:7798, IKBB, TRIP9

Application Details

Application Notes: ELISA titre: 1:62500 . Western Blotting: Suggested dilution at 1.25 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody.

Restrictions: For Research Use only

Images

anti-NFKBIB / IKBB antibody

Publications

Publications: Lee, Allport, Sykes et al.: "The effects of labour and of interleukin 1 beta upon the expression of nuclear factor kappa B related proteins in human amnion." in: Molecular human reproduction, Vol. 9, Issue 4, pp. 213-8, 2003 (PubMed).