KLHL5 antibody (N-Term)

Catalog No. ABIN183088

This Rabbit Polyclonal antibody specifically detects KLHL5 in WB. It exhibits reactivity toward Human, Rat, Mouse, Dog, Cow, Guinea Pig and Horse.

Quick Overview for KLHL5 antibody (N-Term) (ABIN183088)

Target: KLHL5 (Kelch-Like 5 (KLHL5))

Reactivity: Human, Rat, Mouse, Dog, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLHL5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KLHL5 Antibody

Binding Specificity: N-Term

Sequence: NRGQTGANGG RKFLDPCSLQ LPLASIGYRR SSQLDFQNSP SWPMASTSEV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against KLHL5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KLHL5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 694 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KLHL5

Target: KLHL5 (Kelch-Like 5 (KLHL5))

Alternative Name: KLHL5

Background: The kelch-repeat protein family is a recently found new kind of actin-binding protein. It is characterized by tandemly arranged motifs of about 50 amino acids. Most members of the kelch-repeat family were cytoskeletal proteins implicated in various cellular processes, such as actin cytoskeleton interaction, cytoplasmic sequestration of transcription factors and cell morphology. During the large-scale sequencing analysis of a human fetal brain cDNA library we found a novel kelch-like protein gene 5, KLHL5, KLHL5 has high identity with Drosophila kelch protein and many other family members. A novel splicing variants of KLHL5, named KLHL5b and the expression pattern of KLHL5b in many tissues.
Protein Interaction Partner: FUS, CUL3, UBC, MAP1LC3B, GABARAPL2, TK1, SMN1,
Protein Size: 694

Molecular Weight: 76 kDa

Gene ID: 51088

NCBI Accession: NM_199039, NP_950240

UniProt: Q6Y881