SCNN1B antibody (C-Term)

Catalog No. ABIN183112

This Rabbit Polyclonal antibody specifically detects SCNN1B in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Guinea Pig, Pig, Goat, Horse and Rabbit.

Quick Overview for SCNN1B antibody (C-Term) (ABIN183112)

Target: SCNN1B (Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Pig, Goat, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCNN1B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SCNN1B Antibody

Binding Specificity: C-Term

Sequence: QPDTAPRSPN TGPYPSEQAL PIPGTPPPNY DSLRLQPLDV IESDSEGDAI

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against SCNN1B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SCNN1B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 640 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SCNN1B

Target: SCNN1B (Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B))

Alternative Name: SCNN1B

Background: When expressed in the bladder epithelium, the protein encoded by the SCNN1B gene might be implicated in the mechanosensory transduction in the bladder afferent pathways, thereby inducing detrusor instability by outlet obstruction. Common variants of this gene confer susceptibility to human essential hypertension.
Alias Symbols: BESC1, ENaCb, SCNEB, ENaCbeta
Protein Interaction Partner: NEDD4L, SERP1, SCNN1G, SCNN1A, COMMD1, UBC, USP2, RAF1, NEDD4, TSC22D3, SGK1, EPN1, AP1M2, NFASC, CNTN1, WWP2, SCNN1D, ANK3, STX1A, ITCH, HECW1,
Protein Size: 640

Molecular Weight: 70 kDa

Gene ID: 6338

NCBI Accession: NM_000336, NP_000327

UniProt: P51168