SCNN1B antibody (C-Term)

Catalog No. ABIN6264946

Product Details anti-SCNN1B Antibody

Target: SCNN1B (Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCNN1B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: SCNN1B Antibody detects endogenous levels of total SCNN1B.

Predicted Reactivity: Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SCNN1B, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for SCNN1B

Target: SCNN1B (Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B))

Alternative Name: SCNN1B (SCNN1B Products)

Synonyms: BESC1 antibody, ENaCb antibody, ENaCbeta antibody, SCNEB antibody, RNENACB antibody, besc1 antibody, betaxENaC antibody, enacb antibody, enacbeta antibody, scnn1b antibody, beta-ENaC antibody, scneb antibody, SCNN1B antibody, BETA-ENAC antibody, sodium channel epithelial 1 beta subunit antibody, sodium channel, non voltage gated 1 beta subunit L homeolog antibody, sodium channel, non voltage gated 1 beta subunit antibody, sodium channel, nonvoltage-gated 1 beta antibody, sodium channel, non voltage gated 1 beta subunit S homeolog antibody, SCNN1B antibody, Scnn1b antibody, scnn1b.L antibody, scnn1b antibody, scnn1b.S antibody

Background:

Description: Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.

Gene: SCNN1B

Molecular Weight: 73kDa

Gene ID: 6338

UniProt: P51168