CLIC1 antibody (N-Term)

Catalog No. ABIN183126

This anti-CLIC1 antibody is a Rabbit Polyclonal antibody detecting CLIC1 in WB and IHC. Suitable for Human, Rat, Mouse, Cow, Goat, Horse, Guinea Pig, Rabbit, Dog and Zebrafish (Danio rerio). This Primary Antibody has been cited in 1 publication.

Quick Overview for CLIC1 antibody (N-Term) (ABIN183126)

Target: CLIC1 (Chloride Intracellular Channel 1 (CLIC1))

Reactivity: Human, Rat, Mouse, Cow, Goat, Horse, Guinea Pig, Rabbit, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLIC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CLIC1 Antibody

Binding Specificity: N-Term

Sequence: GQLPFLLYGT EVHTDTNKIE EFLEAVLCPP RYPKLAALNP ESNTAGLDIF

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against CLIon Channel1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CLIC1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 241 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-CLIC1 antibody (ABIN183126)

Yang, Jung, Cho, Choi, Kim, Kim, Kim, Jang, Lee, Han, Shin: "Chloride intracellular channel 1 regulates osteoblast differentiation." in: Bone, Vol. 45, Issue 6, pp. 1175-85, (2009) (PubMed).

Target Details for CLIC1

Target: CLIC1 (Chloride Intracellular Channel 1 (CLIC1))

Alternative Name: CLIC1

Background: Chloride intracellular channel 1 is a member of the p64 family, a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH , and regulation of cell volume. CLIon Channel1 encodes a protein that localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.
Alias Symbols: G6, NCC27
Protein Interaction Partner: UBC, PSMD10, SUMO2, SUMO1, NEDD8, FBXO6, ZNF302, NUP62, PRDX4, IKBKG, ZNF184, VCAM1, THRA, RPLP1, NTF4, ITGA4, FN1, ATF2, CPT1A, ATP6V0A1, ATP6V0C, ATP5F1, ALOX5AP, GRK5, MYOC, CDK2, ISG15, ARRB2, SUMO4, LSM1, AKAP9, TRAPPC2,
Protein Size: 241

Molecular Weight: 27 kDa

Gene ID: 1192

NCBI Accession: NM_001288, NP_001279

UniProt: Q502X1