CLIC1 antibody (N-Term)

Catalog No. ABIN2776130

Cited in 1 publication. The Rabbit Polyclonal anti-CLIC1 antibody (ABIN2776130) specifically detects CLIC1 in WB and IHC. The antibody is reactive with Human, Rat, Mouse, Cow, Goat, Horse, Guinea Pig, Rabbit, Dog and Zebrafish (Danio rerio) samples.

Quick Overview for CLIC1 antibody (N-Term) (ABIN2776130)

Target: CLIC1 (Chloride Intracellular Channel 1 (CLIC1))

Reactivity: Human, Rat, Mouse, Cow, Goat, Horse, Guinea Pig, Rabbit, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLIC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CLIC1 Antibody

Binding Specificity: N-Term

Purpose: CLIC1 Antibody - N-terminal region

Sequence: GQLPFLLYGT EVHTDTNKIE EFLEAVLCPP RYPKLAALNP ESNTAGLDIF

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against CLIon Channel1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CLIC1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP35045-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-CLIC1 antibody (ABIN2776130)

Yang, Jung, Cho, Choi, Kim, Kim, Kim, Jang, Lee, Han, Shin: "Chloride intracellular channel 1 regulates osteoblast differentiation." in: Bone, Vol. 45, Issue 6, pp. 1175-85, (2009) (PubMed).

Target Details for CLIC1

Target: CLIC1 (Chloride Intracellular Channel 1 (CLIC1))

Alternative Name: CLIC1

Background:

Background Information: Chloride intracellular channel 1 is a member of the p64 family, a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH , and regulation of cell volume. CLIon Channel1 encodes a protein that localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.

Gene Name: Chloride intracellular channel 1

Alternative Symbols: G6, CL1C1, NCC27, CLCNL1

Protein Name: Chloride intracellular channel protein 1

Molecular Weight: 27 kDa

Gene ID: 1192

NCBI Accession: NP_001279

UniProt: Q502X1