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Details for Product No. ABIN183126

Chloride Intracellular Channel 1 (CLIC1) (N-Term) antibody

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Synonyms G6, NCC27, Clcp, zgc:77044, wu:fc30e04, ncc27, xclic1, MGC75951, MGC132377, CLIC1
»Alternatives N-Term
»Alternatives Rabbit, Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Pig (Porcine), Zebrafish (Danio rerio), Xenopus laevis, Human
»Alternatives Rabbit
Clonality Polyclonal
»Alternatives Un-conjugated
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN183126
Quantity 100 µg
229.00 $   Plus shipping costs $45.00
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Immunogen The immunogen for anti-CLIC1 antibody: synthetic peptide directed towards the N terminal of human CLIC1
Predicted Reactivity Bovine : 100%, Goat : 100%, Human : 100%, Mouse : 100%, Pig : 100%, Rabbit : 100%, Rat : 100%, Zebrafish : 92%
Characteristics This is a rabbit polyclonal antibody against CLIon Channel1. It was validated on Western Blot and immunohistochemistry. We manufacture rabbit polyclonal antibodies on a large scale of high throughput manner. Our antibodies are peptide based and protein family oriented.
Purification Protein A purified
Alternative Name CLIC1
Background Chloride intracellular channel 1 is a member of the p64 family, a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. CLIon Channel1 encodes a protein that localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.
Molecular Weight 27kDa
Gene ID 1192
NCBI Accession NP_001279, NM_001288
UniProt Q502X1
Research Area Signaling, Metabolism
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-CLIC1 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Novarino, Fabrizi, Tonini et al.: "Involvement of the intracellular ion channel CLIC1 in microglia-mediated beta-amyloid-induced neurotoxicity." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 24, Issue 23, pp. 5322-30, 2004 (PubMed).

Alternatives for antigen "Chloride Intracellular Channel 1 (CLIC1)", type "Antibodies"
Hosts (35), (21)
Reactivities (52), (16), (16), (13), (12), (1)
Applications (45), (30), (16), (13), (10), (6), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (8), (7), (4), (4), (2), (1)