GJD2 antibody (Middle Region)

Catalog No. ABIN183391

This Rabbit Polyclonal antibody specifically detects GJD2 in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for GJD2 antibody (Middle Region) (ABIN183391)

Target: GJD2 (Gap Junction Protein, delta 2, 36kDa (GJD2))

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GJD2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GJD2 Antibody

Binding Specificity: Middle Region

Sequence: NTSKETEPDC LEVKELTPHP SGLRTASKSK LRRQEGISRF YIIQVVFRNA

Predicted Reactivity: Cow: 100%, Dog: 88%, Guinea Pig: 88%, Horse: 88%, Human: 100%, Mouse: 88%, Rabbit: 86%, Rat: 88%

Characteristics: This is a rabbit polyclonal antibody against CX36. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CX36

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 321 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GJD2

Target: GJD2 (Gap Junction Protein, delta 2, 36kDa (GJD2))

Alternative Name: CX36

Background: GJA9, also called connexin-36 (CX36), is a member of the connexin gene family that is expressed predominantly in mammalian neurons. Connexins associate in groups of 6 and are organized radially around a central pore to form connexons. Each gap junction intercellular channel is formed by the conjunction of 2 connexons. See GJB2 (MIM 121011) for additional background information on connexins.[supplied by OMIM].
Alias Symbols: CX36, GJA9
Protein Size: 321

Molecular Weight: 35 kDa

Gene ID: 57369

NCBI Accession: NM_020660, NP_065711

UniProt: Q9UKL4