TRPM3 antibody (N-Term)

Catalog No. ABIN183400

Product Details anti-TRPM3 Antibody

Target: TRPM3 (Transient Receptor Potential Cation Channel, Subfamily M, Member 3 (TRPM3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRPM3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TPPVPVVVCD GSGRASDILA FGHKYSEEGG LINESLRDQL LVTIQKTFTY

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against TRPM3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TRPM3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 323 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TRPM3 antibody (ABIN183400)

Takumida, Ishibashi, Hamamoto, Hirakawa, Anniko: "Expression of transient receptor potential channel melastin (TRPM) 1-8 and TRPA1 (ankyrin) in mouse inner ear." in: Acta oto-laryngologica, Vol. 129, Issue 10, pp. 1050-60, (2011) (PubMed).

Target Details for TRPM3

Target: TRPM3 (Transient Receptor Potential Cation Channel, Subfamily M, Member 3 (TRPM3))

Alternative Name: TRPM3 (TRPM3 Products)

Background: The product of the TRPM3 gene belongs to the family of transient receptor potential (TRP) channels. TRP channels are cation-selective channels important for cellular calcium signaling and homeostasis. The protein encoded by TRPM3 mediates calcium entry, and this entry is potentiated by calcium store depletion.
Alias Symbols: GON-2, MLSN2, LTRPC3
Protein Size: 323

Molecular Weight: 36 kDa

Gene ID: 80036

NCBI Accession: NM_001007470

UniProt: Q504Y1