ARX (Middle Region) antibody

Details for Product No. ABIN183405
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Antigen
Synonyms CT121, EIEE1, ISSX, MRX29, MRX32, MRX33, MRX36, MRX38, MRX43, MRX54, MRX76, MRX87, MRXS1, PRTS, RGD1562672
Epitope
Middle Region
(32), (16), (13), (8), (4), (4), (3), (2), (2), (1), (1), (1)
Reactivity
Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(64), (21), (9), (3), (2), (1)
Host
Rabbit
(65), (10), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(6), (6), (6), (6), (6), (6)
Application
Western Blotting (WB)
(52), (51), (16), (9), (3), (2), (1), (1)
Pubmed 4 references available
Quantity 100 μg
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Immunogen Synthetic peptide directed towards the middle region of mouse ARX
Sequence TGAEDDEEEL LEDEEDEEEE EELLEDDDEE LLEDDARALL KEPRRCSVAT
Predicted Reactivity Mouse : 100 %, Dog : 90 %, Guinea pig : 90 %, Human : 90 %, Rabbit : 90 %, Rat : 90 %, Horse : 70 %
Characteristics This is a rabbit polyclonal antibody against ARX. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Background ARX (Aristaless-related genes), a subset of the Paired-related homeobox genes, is a group of regulators of essential events during vertebrate embryogenesis. Arx was highly conserved between mouse and zebrafish. Studies have disclosed its neuromeric expression in the forebrain and longitudinal expression in the floor plate in mouse and zebrafish. It is also expressed in the dorsal telencephalon (presumptive cerebral cortex) of mouse embryos.
Molecular Weight 58 kDa
Gene ID 11878
NCBI Accession NM_007492, NP_031518
UniProt O35085
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 564 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-ARX (Middle Region) antibody WB Suggested Anti-ARX Antibody Titration: 2.5ug/ml
ELISA Titer: 1:15...
Product cited in: Price, Yoo, Burgess et al.: "A triplet repeat expansion genetic mouse model of infantile spasms syndrome, Arx(GCG)10+7, with interneuronopathy, spasms in infancy, persistent seizures, and adult cognitive and behavioral ..." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 27, pp. 8752-63, 2009 (PubMed).

Condomines, Hose, Rème et al.: "Gene expression profiling and real-time PCR analyses identify novel potential cancer-testis antigens in multiple myeloma." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 2, pp. 832-40, 2009 (PubMed).

Background publications Hirata, Nakazawa, Yoshihara et al.: "Zinc-finger gene Fez in the olfactory sensory neurons regulates development of the olfactory bulb non-cell-autonomously." in: Development (Cambridge, England), Vol. 133, Issue 8, pp. 1433-43, 2006 (PubMed).

General Hirata, Nakazawa, Muraoka et al.: "Zinc-finger genes Fez and Fez-like function in the establishment of diencephalon subdivisions." in: Development (Cambridge, England), Vol. 133, Issue 20, pp. 3993-4004, 2006 (PubMed).

Validation Images
Catalog No. ABIN183405
229.00 $
Plus shipping costs $45.00
Quantity
Price
100 μg
229.00 $

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