Interferon Regulatory Factor 5 (IRF5) antibody
| Antigen |
|
| Synonyms |
SLEB10, mirf5, AW491843, MGC76986, zgc:76986, im:7155364, IRF5, irf5 |
| Clonality |
Polyclonal |
|
Host
|
|
|
Reactivity
|
Human (45), Mouse (Murine) (18), Rat (Rattus) (11), Cow (Bovine) (7), Dog (Canine) (3), Chicken (2), Pig (Porcine) (2), Cat (Feline) (1), Rabbit (1), Xenopus laevis (1), Zebrafish (1)
|
|
Application
|
Western Blotting (WB) (42), ELISA (31), Immunoprecipitation (IP) (15), Immunohistochemistry (IHC) (12), Immunofluorescence (IF) (7), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5), Immunocytochemistry (ICC) (3), Chromatin Immunoprecipitation (ChIP) (2), Blocking Antibody (Inhibition) (1), Enzyme Immunoassay (EIA) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
|
| Catalog no. |
ABIN183457 |
| Quantity |
50 µg (Variants) |
| Price |
317.90 $ Plus shipping costs $45.00
|
|
Bulk discount
|
| Shipping to |
|
| Availability |
Will be delivered in 2 to 3 Business Days |
|
Alternative name
|
IRF5
|
|
Gene ID
|
IRF5
|
|
UniProt
|
P56477
|
|
Immunogen
|
The immunogen for anti-IRF5 antibody: synthetic peptide directed towards the N terminal of mouse IRF5
|
|
Sequence
|
CSNGPAPTESQPTDDYVLGEEEEEEEEELQRMLPGLSITE PALPGPPNAP
|
|
Cross-Reactivity
|
Mouse (Murine), Rat (Rattus)
|
|
Format
|
Lyophilized
|
|
Reconstitution
|
Add 50 µl of distilled water. Final anti-IRF5 antibody concentration is 1 mg/ml.
|
|
Description
|
The activation of Toll-like receptors (TLRs) is central to innate and adaptive immunity. All TLRs use the adaptor MyD88 for signaling. IRF-5 is generally involved downstream of the TLR-MyD88 signalling pathway for gene induction of proinflammatory cytokines, such as interleukin-6 (IL-6), IL-12 and tumour-necrosis factor-alpha.
|
|
Characteristics
|
Antigen Size: 497 amino acids
|
|
Molecular Weight
|
55kDa
|
|
Application Notes
|
WB Suggested Anti-IRF5 Antibody Titration: 0.15ug/ml
ELISA Titer: 1:62500
Positive Control: Human Lymphnode.
|
|
Purification
|
Affinity Purified
|
|
Buffer
|
PBS
|
|
Storage (Long Term)
|
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
|
|
Storage (Short Term)
|
Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
|
|
Research Area
|
Chromatin and Nuclear Signaling, Transcription Factors, Innate Immunity, Cytokines
|
|
Restrictions
|
For Research Use only
|
|
Product
|
Takaoka, Yanai, Kondo et al.: "Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors." in: Nature, Vol. 434, Issue 7030, pp. 243-9, 2005 (PubMed).
|
Alternatives for antigen "Interferon Regulatory Factor 5 (IRF5)", type "Antibodies"
|
Hosts
|
Rabbit (19), Mouse (18), Goat (8), Sheep (1)
|
|
Reactivities
|
Human (45), Mouse (Murine) (18), Rat (Rattus) (11), Cow (Bovine) (7), Dog (Canine) (3), Chicken (2), Pig (Porcine) (2), Cat (Feline) (1), Rabbit (1), Xenopus laevis (1), Zebrafish (1)
|
|
Applications
|
Western Blotting (WB) (42), ELISA (31), Immunoprecipitation (IP) (15), Immunohistochemistry (IHC) (12), Immunofluorescence (IF) (7), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5), Immunocytochemistry (ICC) (3), Chromatin Immunoprecipitation (ChIP) (2), Blocking Antibody (Inhibition) (1), Enzyme Immunoassay (EIA) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
|
|
Epitopes
|
N-Term (5), C-Term (4), AA 176-240 (2), Internal Region (1)
|
Alternatives 
