SRP14 antibody (N-Term)

Catalog No. ABIN183958

This Rabbit Polyclonal antibody specifically detects SRP14 in WB and IHC. It exhibits reactivity toward Human, Rat, Dog, Mouse, Cow, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit and Sheep.

Quick Overview for SRP14 antibody (N-Term) (ABIN183958)

Target: SRP14 (Signal Recognition Particle 14kDa (Homologous Alu RNA Binding Protein) (SRP14))

Reactivity: Human, Rat, Dog, Mouse, Cow, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRP14 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SRP14 Antibody

Binding Specificity: N-Term

Sequence: KPIPKKGTVE GFEPADNKCL LRATDGKKKI STVVSSKEVN KFQMAYSNLL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against SRP14. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SRP14

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 136 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SRP14

Target: SRP14 (Signal Recognition Particle 14kDa (Homologous Alu RNA Binding Protein) (SRP14))

Alternative Name: SRP14

Background: SRP14 belongs to the SRP14 family. The signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
Alias Symbols: ALURBP
Protein Interaction Partner: HUWE1, ITGB1BP2, UBC, MDM2, LIN28A, ASB3, EED, BMI1, PKM, CBS, P3H1, IPO9, NPLOC4, DPP8, LARS, SZRD1, WDR4, PDLIM5, PLIN3, SAE1, UBA2, EIF4A3, ANP32A, SRP9, IGSF8, EEF2K, ICAM1, PAN2, IL7R, FN1, METTL18, SRP54, PRPF19, SRRM2, ACIN1, RPL14, SNRPD1, SNRPA1,
Protein Size: 136

Molecular Weight: 15 kDa

Gene ID: 6727

NCBI Accession: NM_003134, NP_003125

UniProt: P37108