U1 SnRNP Protein A (0) antibody

Antigen: U1 SnRNP Protein A (0)

Synonyms: U1A, Rnu1a1, Rnu1a-1, C430021M15Rik, SNRPA, MGC137110

Clonality: Polyclonal

Host: Rabbit

Reactivity: Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Catalog no.: ABIN183974

Additional Information

Alternative name: U1 snRNP protein A

Description: SNRPA binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. Keywords: SNRPA, small nuclear ribonucleoprotein polypeptide A, ARP40531_P050, NP_004587, NM_004596, P09012, U1A

Application Details

Application Notes: ELISA titre: 1:312500 . Western Blotting: Suggested dilution at 0.5 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody.

Restrictions: For Research Use only

Images

anti-U1 SnRNP Protein A (0) antibody

anti-U1 SnRNP Protein A (0) antibody (Image 2)

anti-U1 SnRNP Protein A (0) antibody (Image 3)

Publications

Publications: Shajani, Varani: "13C NMR relaxation studies of RNA base and ribose nuclei reveal a complex pattern of motions in the RNA binding site for human U1A protein." in: Journal of molecular biology, Vol. 349, Issue 4, pp. 699-715, 2005 (PubMed).