Cholinergic Receptor, Nicotinic, alpha 2 (Neuronal) (CHRNA2) antibody

Antigen: Cholinergic Receptor, Nicotinic, alpha 2 (Neuronal) (CHRNA2)

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB)

Catalog no.: ABIN184249

Additional Information

Alternative name: Neuronal acetylcholine receptor subunit alpha-2

Gene ID: CHRNA2

UniProt: Q15822

Immunogen: The immunogen for anti-CHRNA2 antibody: synthetic peptide directed towards the N terminal of human CHRNA2

Sequence: TKLSLWWLLLTPAGGEEAKRPPPRAPGDPLSSPSPTALPQ GGSHTETEDR

Cross-Reactivity: Human

Format: Lyophilized

Reconstitution: Add 100 µl of distilled water. Final anti-CHRNA2 antibody concentration is 1 mg/ml.

Description: After binding acetylcholine, the ACHR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

Characteristics: Antigen Size: 529 amino acids

Molecular Weight: 60kDa

Application Details

Purification: Protein A purified

Buffer: PBS

Storage (Long Term): For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.

Storage (Short Term): Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.

Restrictions: For Research Use only

Images

anti-Cholinergic Receptor, Nicotinic, alpha 2 (Neuronal) (CHRNA2) antibody

Publications

Product: Elliott, Ellis, Berckhan et al.: "Comparative structure of human neuronal alpha 2-alpha 7 and beta 2-beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits." in: Journal of molecular neuroscience : MN, Vol. 7, Issue 3, pp. 217-28, 1997 (PubMed).