HMOX2 antibody (N-Term)

Catalog No. ABIN184250

The Rabbit Polyclonal anti-HMOX2 antibody is suitable to detect HMOX2 in samples from Human. It has been validated for WB.

Quick Overview for HMOX2 antibody (N-Term) (ABIN184250)

Target: HMOX2 (Heme Oxygenase (Decycling) 2 (HMOX2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMOX2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HMOX2 Antibody

Binding Specificity: N-Term

Sequence: MSAEVETSEG VDESEKKNSG ALEKENQMRM ADLSELLKEG TKEAHDRAEN

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against HMOX2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HMOX2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 316 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HMOX2

Target: HMOX2 (Heme Oxygenase (Decycling) 2 (HMOX2))

Alternative Name: HMOX2

Background: HEME oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed
Alias Symbols: HO-2
Protein Interaction Partner: UBC, MDM2, SKA2, BLOC1S2, ZNF746, ZFP28, ITFG1, JADE1, KIAA1377, NKRF, INPP5K, SNX7, GIT1, SNX5, PLXNB2, IMMT, CEBPZ, HAP1, EIF3C, SHC1, RBBP4, NDUFS2, NR3C1, ATP5B, A2M, USP19, LRIF1, COPS6, KCNMA1, MED31, EEF1G, SETDB1, GPRASP1, CSNK2A1, APP,
Protein Size: 316

Molecular Weight: 36 kDa

Gene ID: 3163

NCBI Accession: NM_002134, NP_002125

UniProt: P30519

Pathways: Transition Metal Ion Homeostasis