CHRNA1 antibody (C-Term)

Catalog No. ABIN184253

The Rabbit Polyclonal anti-CHRNA1 antibody has been validated for WB and IHC. It is suitable to detect CHRNA1 in samples from Human, Mouse, Dog, Guinea Pig, Rabbit and Pig.

Quick Overview for CHRNA1 antibody (C-Term) (ABIN184253)

Target: CHRNA1 (Acetylcholine Receptor Subunit alpha (CHRNA1))

Reactivity: Human, Mouse, Dog, Guinea Pig, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CHRNA1 Antibody

Binding Specificity: C-Term

Sequence: STHVMPNWVR KVFIDTIPNI MFFSTMKRPS REKQDKKIFT EDIDISDISG

Predicted Reactivity: Dog: 100%, Guinea Pig: 86%, Human: 100%, Mouse: 80%, Pig: 100%, Rabbit: 93%

Characteristics: This is a rabbit polyclonal antibody against CHRNA1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CHRNA1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 457 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHRNA1

Target: CHRNA1 (Acetylcholine Receptor Subunit alpha (CHRNA1))

Alternative Name: CHRNA1

Background: CHRNA1 encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha isoforms and 1 each of beta, gamma, and delta subunits.
Alias Symbols: ACHRA, ACHRD, CHRNA, CMS2A, FCCMS, SCCMS
Protein Interaction Partner: ITGA7, CHRND, CHRNG, CHRNE,
Protein Size: 457

Molecular Weight: 52 kDa

Gene ID: 1134

NCBI Accession: NM_000079, NP_000070

Pathways: Skeletal Muscle Fiber Development