CHRNA1 antibody (C-Term)

Catalog No. ABIN2792292

The Rabbit Polyclonal anti-CHRNA1 antibody is suitable to detect CHRNA1 in samples from Human, Mouse, Dog, Guinea Pig, Rabbit and Pig. It has been validated for WB and IHC.

Quick Overview for CHRNA1 antibody (C-Term) (ABIN2792292)

Target: CHRNA1 (Acetylcholine Receptor Subunit alpha (CHRNA1))

Reactivity: Human, Mouse, Dog, Guinea Pig, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CHRNA1 Antibody

Binding Specificity: C-Term

Purpose: CHRNA1 Antibody - C-terminal region

Sequence: STHVMPNWVR KVFIDTIPNI MFFSTMKRPS REKQDKKIFT EDIDISDISG

Predicted Reactivity: Dog: 100%, Guinea Pig: 86%, Human: 100%, Mouse: 80%, Pig: 100%, Rabbit: 93%

Characteristics: This is a rabbit polyclonal antibody against CHRNA1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CHRNA1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHRNA1

Target: CHRNA1 (Acetylcholine Receptor Subunit alpha (CHRNA1))

Alternative Name: CHRNA1

Background:

Targeted Subunit: alpha

Background Information: CHRNA1 encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha isoforms and 1 each of beta, gamma, and delta subunits.

Gene Name: Cholinergic receptor, nicotinic, alpha 1 (muscle)

Alternative Symbols: ACHRA, ACHRD, CHRNA, CMS1A, CMS1B, CMS2A, FCCMS, SCCMS

Protein Name: Acetylcholine receptor subunit alpha

Molecular Weight: 52kDa

Gene ID: 1134

NCBI Accession: NP_000070

UniProt: P02708

Pathways: Skeletal Muscle Fiber Development