CHRNA1 antibody (C-Term)

Catalog No. ABIN2792292

Product Details anti-CHRNA1 Antibody

Target: CHRNA1 (Acetylcholine Receptor Subunit alpha (CHRNA1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Dog, Rabbit, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: STHVMPNWVR KVFIDTIPNI MFFSTMKRPS REKQDKKIFT EDIDISDISG

Predicted Reactivity: Dog: 100%, Guinea Pig: 86%, Human: 100%, Mouse: 80%, Pig: 100%, Rabbit: 93%

Characteristics: This is a rabbit polyclonal antibody against CHRNA1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CHRNA1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 457 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHRNA1

Target: CHRNA1 (Acetylcholine Receptor Subunit alpha (CHRNA1))

Alternative Name: CHRNA1 (CHRNA1 Products)

Synonyms: CHRNA1 antibody, ACHRA antibody, ACHRD antibody, CHRNA antibody, CMS2A antibody, FCCMS antibody, SCCMS antibody, NACHRA1 antibody, AI385656 antibody, AI608266 antibody, Achr-1 antibody, Acra antibody, cholinergic receptor nicotinic alpha 1 subunit antibody, cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle) antibody, CHRNA1 antibody, Chrna1 antibody

Background: CHRNA1 encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha isoforms and 1 each of beta, gamma, and delta subunits.
Alias Symbols: ACHRA, ACHRD, CHRNA, CMS2A, FCCMS, SCCMS
Protein Interaction Partner: ITGA7, CHRND, CHRNG, CHRNE,
Protein Size: 457

Molecular Weight: 52 kDa

Gene ID: 1134

NCBI Accession: NM_000079, NP_000070

Pathways: Skeletal Muscle Fiber Development