Prostaglandin-Endoperoxide Synthase 2 (PTGS2) antibody

Antigen: Prostaglandin-Endoperoxide Synthase 2 (PTGS2)

Synonyms: COX2, COX-2, PHS-2, PGG/HS, PGHS-2, hCox-2, GRIPGHS, Cox-2, Pghs2, TIS10, Cox2, ptgs2, zCOX-2, fj02a10, unp1239, wu:fj02a10, PTGS2, cox2, cox-2, MGC80431, phs-2, hcox-2, pgg/hs, pghs-2, MGC97821, PGHS2, Ptgs2

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN184672

Additional Information

Alternative name: COX2 / PTGS2

Gene ID: 5743

Immunogen: C-NPTVLLKERSTEL

Format: Affinity-purified

Description: All names and symbols: PTGS2, COX2, prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase), COX-2, PHS-2, PGG/HS, PGHS-2, hCox-2, prostaglandin G/H synthase and cyclooxygenase. Official Symbol: PTGS2. RefSeq number(s): NP_000954.1. Gene ontology terms: cytoplasm, cell motility, inflammatory response, physiological processes, prostaglandin metabolism, prostaglandin-endoperoxide synthase

Specificity: Human, Dog, Sheep, Cow, Pig

Synonyms: COX2, COX-2, PHS-2, PGG/HS, PGHS-2, hCox-2, GRIPGHS, Cox-2, Pghs2, TIS10, Cox2, ptgs2, zCOX-2, fj02a10, unp1239, wu:fj02a10, PTGS2, cox2, cox-2, MGC80431, phs-2, hcox-2, pgg/hs, pghs-2, MGC97821, PGHS2, Ptgs2

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution >1:32,000. Western Blot: Approx 70-75kDa band observed in H460 lysates (predicted MW of 69kDa according to NP_000954.1). Recommended for use at 0.5-2µg/ml.

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Restrictions: For Research Use only

Images

ABIN184672 staining (0.5µg/ml) of H460 lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Publications

Publications: Ballif, Mincek, Barratt et al.: "Interaction of cyclooxygenases with an apoptosis- and autoimmunity-associated protein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 11, pp. 5544-9, 1996 (PubMed).