PTGS2 antibody (AA 375-604)
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- Target See all PTGS2 Antibodies
- PTGS2 (Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2))
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Binding Specificity
- AA 375-604
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PTGS2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Sequence
- PLLPDTFQIH DQKYNYQQFI YNNSILLEHG ITQFVESFTR QIAGRVAGGR NVPPAVQKVS QASIDQSRQM KYQSFNEYRK RFMLKPYESF EELTGEKEMS AELEALYGDI DAVELYPALL VEKPRPDAIF GETMVEVGAP FSLKGLMGNV ICSPAYWKPS TFGGEVGFQI INTASIQSLI CNNVKGCPFT SFSVPDPELI KTVTINASSS RSGLDDINPT VLLKERSTEL
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 375-604 of human COX2/PTGS2 (NP_000954.1).
- Isotype
- IgG
- Top Product
- Discover our top product PTGS2 Primary Antibody
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- Application Notes
- WB,1:1000 - 1:4000,IHC,1:50 - 1:200,IF,1:50 - 1:100
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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Curcumin Attenuates Colistin-Induced Neurotoxicity in N2a Cells via Anti-inflammatory Activity, Suppression of Oxidative Stress, and Apoptosis." in: Molecular neurobiology, Vol. 55, Issue 1, pp. 421-434, (2018) (PubMed).
: "Ceramide enhances COX-2 expression and VSMC contractile hyperreactivity via ER stress signal activation." in: Vascular pharmacology, Vol. 96-98, pp. 26-32, (2017) (PubMed).
: "Rhizoma Smilacis Glabrae inhibits pathogen-induced upper genital tract inflammation in rats through suppression of NF-κB pathway." in: Journal of ethnopharmacology, Vol. 202, pp. 103-113, (2017) (PubMed).
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Curcumin Attenuates Colistin-Induced Neurotoxicity in N2a Cells via Anti-inflammatory Activity, Suppression of Oxidative Stress, and Apoptosis." in: Molecular neurobiology, Vol. 55, Issue 1, pp. 421-434, (2018) (PubMed).
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- Target
- PTGS2 (Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2))
- Alternative Name
- PTGS2 (PTGS2 Products)
- Synonyms
- COX-2 antibody, COX2 antibody, GRIPGHS antibody, PGG/HS antibody, PGHS-2 antibody, PHS-2 antibody, hCox-2 antibody, Cox-2 antibody, Pghs2 antibody, TIS10 antibody, Cox2 antibody, cox-2 antibody, CEF147 antibody, PGHS2 antibody, PHSII antibody, cox2 antibody, gripghs antibody, pgg/hs antibody, pghs-2 antibody, phs-2 antibody, PTGS2 antibody, hcox-2 antibody, fj02a10 antibody, ptgs2 antibody, unp1239 antibody, wu:fj02a10 antibody, zCOX-2 antibody, si:dkey-97o5.6 antibody, prostaglandin-endoperoxide synthase 2 antibody, prostaglandin G/H synthase 2 antibody, prostaglandin-endoperoxide synthase 2S homeolog antibody, prostaglandin-endoperoxide synthase 2a antibody, prostaglandin-endoperoxide synthase 2b antibody, PTGS2 antibody, Ptgs2 antibody, LOC100136456 antibody, ptgs2.S antibody, ptgs2 antibody, ptgs2a antibody, ptgs2b antibody
- Background
- Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.,PTGS2,COX-2,COX2,GRIPGHS,PGG/HS,PGHS-2,PHS-2,hCox-2,Cox2,Cancer,Tumor biomarkers,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Cardiovascular,Blood,Lipids,PTGS2
- Molecular Weight
- 68 kDa
- Gene ID
- 5743
- UniProt
- P35354
- Pathways
- Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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