Engulfment and Cell Motility 2 (ELMO2) antibody

Antigen: Engulfment and Cell Motility 2 (ELMO2)

Synonyms: CED12, CED-12, ELMO-1, KIAA0281, MGC126406, ELMO-2, FLJ11656, KIAA1834, elmo2, MGC89478, ELMO2, MGC109347, MGC137761, MGC114811, DKFZp469C2416

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN184684

Additional Information

Alternative name: ELMO2

Gene ID: 63916, 140579 (mouse)

Immunogen: C-PKEPSSYDFVYHYG

Format: Affinity-purified

Description: All names and symbols: ELMO2, engulfment and cell motility 2 (ced-12 homolog, C. elegans), CED12, FLJ11656, KIAA1834, ced-12 homolog 2, PH domain protein CED12A, engulfment and cell motility 2. Official Symbol: ELMO2. RefSeq number(s): NP_877496.1, NP_573403.1

Specificity: NP_877496.1 and NP_573403.1 are varients that encode the same protein. Human, Mouse 720 aa, 720 aa

Application Details

Application Notes: Western blot: Approx 80kDa band seen in Human Brain lysate. Recommended for use at 1-3µg/ml.

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Restrictions: For Research Use only

Images

ABIN184684 staining (2µg/ml) of Human Brain lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 12 hour. Detected by western blot using chemiluminescence.

Publications

Publications: Gumienny, Brugnera, Tosello-Trampont et al.: "CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration." in: Cell, Vol. 107, Issue 1, pp. 27-41, 2001 (PubMed).