G Protein Pathway Suppressor 1 (GPS1) antibody

Antigen: G Protein Pathway Suppressor 1 (GPS1)

Synonyms: CSN1, COPS1, MGC71287

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN184996

Additional Information

Alternative name: GPS1 / COPS1

Gene ID: 2873, 209318 (mouse), 117039 (rat)

Immunogen: C-PANSQSRMSTNM

Format: Affinity-purified

Description: All names and symbols: GPS1, COPS1, G protein pathway suppressor 1, Arabidopsis FUS6/COP11 homolog. Official Symbol: GPS1. RefSeq number(s): NP_004118. Gene ontology terms: GTPase inhibitor activity, JNK cascade, inactivation of MAPK, cell cycle

Specificity: Human, Mouse, Rat 500 aa

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution >1:32,000. Western Blot: Approx 55kDa band observed in Human Testis lysate (predicted MW of 58kDa according to NP_004118). Recommended for use at 0.5µg/ml.

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Restrictions: For Research Use only

Images

ABIN184996 staining (0.5µg/ml) of Human Testis lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Publications

Publications: Spain, Bowdish, Pacal et al.: "Two human cDNAs, including a homolog of Arabidopsis FUS6 (COP11), suppress G-protein- and mitogen-activated protein kinase-mediated signal transduction in yeast and mammalian cells." in: Molecular and cellular biology, Vol. 16, Issue 12, pp. 6698-706, 1997 (PubMed).