CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1) antibody

Antigen: CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1)

Synonyms: Oasis, MGC25246, OASIS, MGC94038, CREB3L1

Clonality: Polyclonal

Host: Goat

Application: ELISA

Catalog no.: ABIN185468

Additional Information

Alternative name: OASIS / CREB3L1

Gene ID: 90993

Immunogen: C-DFSHSKEWFHDRD

Format: Affinity-purified

Description: All names and symbols: CREB3L1, OASIS, cAMP responsive element binding protein 3-like 1, BBF-2 (drosophila) homolog, old astrocyte specifically induced substance. Official Symbol: CREB3L1. RefSeq number(s): NP_443086.1. Gene ontology terms: nucleus, regulation of transcription, DNA-dependent, transcription factor activity

Specificity: Human, Mouse, Rat

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:32,000. Western Blot: Preliminary experiments gave an approx 40kDa band in Human Brain lysates after 0.3 µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 57.0kDa according to NP_443086.1. The 40kDa band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Restrictions: For Research Use only

Publications

Publications: Kondo, Murakami, Tatsumi et al.: "OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes." in: Nature cell biology, Vol. 7, Issue 2, pp. 186-94, 2005 (PubMed).