Sirtuin 3 (SIRT3) antibody
| Antigen |
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| Synonyms |
SIR2L3, MGC158774, zgc:158774, SIRT3 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Human (52), Mouse (Murine) (30), Rat (Rattus) (26), Dog (Canine) (20), Pig (Porcine) (18), Rabbit (2), Cat (Feline) (1), Chicken (1), Cow (Bovine) (1), Fruit Fly (Drosophila melanogaster) (1), Xenopus laevis (1), Zebrafish (1)
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Conjugate
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Biotin (4), FITC (3), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
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Application
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| Catalog no. |
ABIN185498 |
| Quantity |
100 ug |
| Price |
374.27 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Ships within 5 Business Days |
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Alternative name
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SIRT3
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Gene ID
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23410
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Immunogen
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C-QRETGKLDGPDK
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Description
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All names and symbols: SIRT3, sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae) , HGNC:14931, SIR2L3 , mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase, silent mating type information regulation 2, S.cerevisiae, homolog 3, sir2-like 3, sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 3, sirtuin 3, sirtuin type 3. Official Symbol: SIRT3. RefSeq number(s): NP_036371.1, NP_001017524.1
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Specificity
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This antibody is expected to recognize both reported isoforms (NP_036371.1 and NP_001017524.1). Human
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Application Notes
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Peptide ELISA: antibody detection limit dilution 1:128,000. Western Blot: Approx 28kDa band observed in Human Liver lysates (calculated MW of 28.6kDa according to NP_001017524.1). Recommended concentration: 0.1-0.3µg/ml.
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Purification
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Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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Buffer
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0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
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Storage
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Aliquot and store at -20°C. Minimize freezing and thawing.
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Research Area
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Cancer, Proteases
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Restrictions
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For Research Use only
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Shi, Wang, Stieren et al.: "SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes." in: The Journal of biological chemistry, Vol. 280, Issue 14, pp. 13560-7, 2005 (PubMed).
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Alternatives for antigen "Sirtuin 3 (SIRT3)", type "Antibodies"
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Hosts
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Rabbit (54), Chicken (5), Goat (5), Mouse (1)
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Reactivities
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Human (52), Mouse (Murine) (30), Rat (Rattus) (26), Dog (Canine) (20), Pig (Porcine) (18), Rabbit (2), Cat (Feline) (1), Chicken (1), Cow (Bovine) (1), Fruit Fly (Drosophila melanogaster) (1), Xenopus laevis (1), Zebrafish (1)
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Applications
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Western Blotting (WB) (43), ELISA (33), Immunofluorescence (IF) (17), Immunohistochemistry (IHC) (11), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunocytochemistry (ICC) (2), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1)
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Conjugates
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Biotin (4), FITC (3), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
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Epitopes
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C-Term (14), Internal Region (6), N-Term (2), AA 203-221 (1), AA 265-280 (1), AA 38-7 (1), C-Term,AA 229-259 (1), Center (1), Middle Region (1), N-Term,AA 55-84 (1)
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Alternatives 
