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Adenosine A2a Receptor antibody (ADORA2A) (C-Term)

Details for Product anti-ADORA2A Antibody No. ABIN185549, Supplier: Login to see
Antigen
  • ADORA2A
  • adora2a.1
  • zgc:194773
  • LOC606744
  • A2aR
  • ADORA2
  • RDC8
  • A2AAR
  • AA2AR
  • A2ar
  • ADENO
  • Adora2l1
Alternatives
anti-Rhesus Monkey Adenosine A2a Receptor antibody for ELISA
Epitope
C-Term
26
17
16
13
10
6
4
4
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Rhesus Monkey
117
26
26
11
2
2
2
1
1
Host
Goat
93
18
14
Clonality
Polyclonal
Conjugate
This Adenosine A2a Receptor antibody is un-conjugated
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
Methode Type
Peptide ELISA
Application
ELISA, Western Blotting (WB)
85
55
33
22
14
13
11
10
4
3
2
1
1
1
1
Supplier
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Immunogen Peptide with sequence HELKGVCPEPPGLDD, from the C Terminus of the protein sequence according to NP_000666.2.
Blocking Peptide Blocking peptide for this product available: ABIN370179
Cross-Reactivity Human
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name Adenosine A2a Receptor (ADORA2A Antibody Abstract)
Background Synonyms: ADORA2A, adenosine A2a receptor, HGNC:263, ADORA2, RDC8, hA2aR, adenosine A2 receptor, adenosine receptor subtype A2a
Gene ID 135
NCBI Accession NP_000666
Research Area Cell Cycle, DNA/RNA, Receptors
Pathways Neurotrophin Signaling Pathway
Application Notes ELISA: antibody detection limit dilution 1:8000.
Western blot: This antibody has been successfully used on lysates of primary Rhesus microglia in Van der Putten et al, PMID: 19494284.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Product cited in: van der Putten, Zuiderwijk-Sick, van Straalen et al.: "Differential expression of adenosine A3 receptors controls adenosine A2A receptor-mediated inhibition of TLR responses in microglia." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 12, pp. 7603-12, 2009 (PubMed).

Background publications Rétey, Adam, Honegger et al.: "A functional genetic variation of adenosine deaminase affects the duration and intensity of deep sleep in humans." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 43, pp. 15676-81, 2005 (PubMed).