anti-Adenosine A2a Receptor antibody (ADORA2A) (C-Term)

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Antigen
Synonyms ADORA2A, adora2a.1, zgc:194773, LOC606744, A2aR, ADORA2, RDC8, A2AAR, AA2AR, A2ar, ADENO, Adora2l1
Alternatives
Epitope
C-Term
(27), (19), (16), (13), (10), (6), (4), (4), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Rhesus Monkey
(126), (26), (26), (10), (2), (2), (2), (1), (1)
Host
Goat
(101), (19), (14)
Clonality
Polyclonal
Conjugate
This Adenosine A2a Receptor antibody is un-conjugated
(4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Methode Type Peptide ELISA
Application
ELISA, Western Blotting (WB)
(92), (63), (42), (26), (15), (13), (11), (10), (4), (3), (2), (1), (1), (1), (1)
Pubmed 2 references available
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Quantity 100 μg
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Immunogen Peptide with sequence HELKGVCPEPPGLDD, from the C Terminus of the protein sequence according to NP_000666.2.
Cross-Reactivity Human
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name Adenosine A2a Receptor (ADORA2A Antibody Abstract)
Background Synonyms: ADORA2A, adenosine A2a receptor, HGNC:263, ADORA2, RDC8, hA2aR, adenosine A2 receptor, adenosine receptor subtype A2a
Gene ID 135
NCBI Accession NP_000666
Research Area Cell Cycle, DNA/RNA, Receptors
Pathways Neurotrophin Signaling Pathway
Application Notes ELISA: antibody detection limit dilution 1:8000.
Western blot: This antibody has been successfully used on lysates of primary Rhesus microglia in Van der Putten et al, PMID: 19494284.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Product cited in: van der Putten, Zuiderwijk-Sick, van Straalen et al.: "Differential expression of adenosine A3 receptors controls adenosine A2A receptor-mediated inhibition of TLR responses in microglia." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 12, pp. 7603-12, 2009 (PubMed).

Background publications Rétey, Adam, Honegger et al.: "A functional genetic variation of adenosine deaminase affects the duration and intensity of deep sleep in humans." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 43, pp. 15676-81, 2005 (PubMed).

Catalog No. ABIN185549
$221.76
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