MVP antibody

Catalog No. ABIN187359

The Mouse Monoclonal anti-MVP antibody (Clone MVP-37) (ABIN187359) specifically detects MVP in WB, IF and IHC (p). The antibody is reactive with Human samples.

Quick Overview for MVP antibody (ABIN187359)

Target: MVP (Major Vault Protein (MVP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MVP antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: MVP-37

Product Details anti-MVP Antibody

Specificity: This antibody reacts with an internal epitope of LRP/MVP (p110) accordingly to an increase in the number of vault particles. LRP is strongly overexpressed in various human non-P-glycoprotein MDR tumor cell lines.

Isotype: IgG2b

Application Details

Application Notes: Western blotting: Use at a 1:50 dilution (chemi-luminescence). Immunohistochemistry: Use at a 1:20 to 1:50 dilution on 4% paraformaldehyde fixed cytospin preparations or frozen tissue sections. The following pretreatment is recommended: 10 min. in 20 mM glycine, pH 7.5, and 10 min. in 6 N guanidine hydrochloride in 50 mM Tris-HCl, pH 7.5. MVP-37 performs well on paraffin-embedded tissue sections. The optimal dilution for a specific application should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 1 mL or 0.5 mL of antibody solution containing approximately 250 µg of immunoglobulin per mL. The solution contains protein stabilizer and 0.1% sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for MVP

Target: MVP (Major Vault Protein (MVP))

Alternative Name: Major Vault Protein