TRAIL antibody
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- Target See all TRAIL (TNFSF10) Antibodies
- TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TRAIL antibody is un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
- Recognizes human TRAIL Species Reactivity: Human.
- Immunogen
- Recombinant human soluble TRAIL (Apo-2L)
- Clone
- IIIF6
- Isotype
- IgG2b
- Top Product
- Discover our top product TNFSF10 Primary Antibody
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anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) (AA 39-250) antibody
TNFSF10 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) (AA 185-281) antibodyTNFSF10 Reactivity: Human, Mouse, Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) (AA 95-281) antibodyTNFSF10 Reactivity: Human FACS, Func Host: Mouse Monoclonal 2E5 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) (AA 95-281) antibody (PE)TNFSF10 Reactivity: Human FACS Host: Mouse Monoclonal 2E5 PE
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) (AA 95-281) antibodyTNFSF10 Reactivity: Human FACS Host: Mouse Monoclonal 2E5 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) (AA 115-287) antibodyTNFSF10 Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) (Internal Region) antibodyTNFSF10 Reactivity: Human WB, ELISA, ICC, IF Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) (AA 1-300) antibodyTNFSF10 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) (AA 1-300) antibodyTNFSF10 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) (AA 40-291) antibodyTNFSF10 Reactivity: Mouse WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Western blotting Flow Cytometry Immunohistochemistry: Frozen sections Immunoprecipitation ELISA The optimal dilution for a specific application should be determined by the researcher.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 100 µl of purified antibody in PBS containing 0.02% NaN3. Concentration 1 mg/ml IgG.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
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- Target
- TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))
- Alternative Name
- CD253 / TRAIL (TNFSF10 Products)
- Background
- Tumor necrosis factor (TNF-)-related apoptosis-inducing ligand (TRAIL, APO-2L) is thought to regulate cell death events in the immune system through TRAIL-R1 (DR4) and TRAIL-R2 (DR5), members of the TNF receptor superfamily. Like the death receptors, including Fas and TNF-R, TRAIL-R1 and TRAIL-R2 have death domains in their cytoplasmic tails that recruit proteins to initiate a cell death signaling cascade. TRAIL (APO-2L) is a 34 kDa type II transmembrane protein. TRAIL forms trimers and is a member of the TNF ligand family. Interaction between TRAIL and TRAIL-R1 and/or TRAIL-R2 rapidly induces apoptosis of TRAIL-sensitive cells. TRAIL can be injected into mice without toxic side effects. Many tumor cells are killed by TRAIL and TRAIL is currently being considered as on of the most promising potential new cancer therapeutics.
- Pathways
- Apoptosis, Positive Regulation of Endopeptidase Activity
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