TNC antibody

Catalog No. ABIN187624

This Mouse Monoclonal antibody specifically detects TNC in WB, IP, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for TNC antibody (ABIN187624)

Target: TNC (Tenascin C (TNC))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNC antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: T2H5

Product Details anti-TNC Antibody

Specificity: Species Reactivity: Human, others not tested.

Sterility: 0.2 μm filtered

Immunogen: Protein preparation from a homogenate of a human mammary tumor.

Isotype: IgG1

Application Details

Application Notes: Immunohistochemistry: frozen tissue staining and paraffin section. Immunoprecipiation Western blotting The optimal dilution for a specific application should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Provided as 0.2 µm sterile filtered solution in phosphate buffered saline with 0.08% sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for TNC

Target: TNC (Tenascin C (TNC))

Alternative Name: Tenascin / TNC / HXB

Background: Tenascin is an extracellular matrix glycoprotein which is found in numerous types of tissues, but most predominately in the nervous system. It has been shown to be upregulated at the edge of healing wounds and in the stroma of many tumors. Three trypes of tenascin have been identified, tenascin-C, which was the first to be identified, tenascin-R, which is found almost exclusively in the central nervous system, and tenascin-X, a mammalian tenascin found in some connective tissue and around blood vessels.

Pathways: Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development