LPAR3 antibody (C-Term)

Catalog No. ABIN187789

This Rabbit Polyclonal antibody specifically detects LPAR3 in WB. It exhibits reactivity toward Human.

Quick Overview for LPAR3 antibody (C-Term) (ABIN187789)

Target: LPAR3 (Lysophosphatidic Acid Receptor 3 (LPAR3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LPAR3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LPAR3 Antibody

Binding Specificity: C-Term

Specificity: Reacts with EDG-7. Species Reactivity: Human, other species not tested.

Sterility: 0.2 μm filtered

Immunogen: Synthetic peptide derived from the C-terminal of the EDG-7 receptor.

Application Details

Application Notes: Western Blot: Use at 5-10 µg/ml using a human EDG-7 receptor transfected cell line. The optimal dilution for a specific application should be determined by the researcher.

Restrictions: For Research Use only

Handling

Buffer: Rabbit polyclonal antibody against human EDG-7 (CT). Available at 100 µg/100 µl in PBS with 0.08% sodium azide. Purification: Sterile filtered at 0.2 µm.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for LPAR3

Target: LPAR3 (Lysophosphatidic Acid Receptor 3 (LPAR3))

Alternative Name: EDG-7 / LPAR3

Background: EDG-7 belongs to a family of G-protein coupled receptors whose lignads are lysophospholipids. The ligand for EDG-7 sphingosine-1-phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG-7 is expressed in prostate as well as other tissues.

Pathways: Regulation of Cell Size