RNF135 antibody (C-Term)

Catalog No. ABIN1881754

This Rabbit Polyclonal antibody specifically detects RNF135 in WB. It exhibits reactivity toward Human and has been mentioned in 3+ publications.

Quick Overview for RNF135 antibody (C-Term) (ABIN1881754)

Target: RNF135 (Ring Finger Protein 135 (RNF135))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF135 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB39664

Product Details anti-RNF135 Antibody

Binding Specificity: AA 375-401, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RNF135 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 375-401 amino acids from the C-terminal region of human RNF135.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:500. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-RNF135 antibody (ABIN1881754)

Zhao, Li, Bradfield, Zhang, Mentch, Wang, Sleiman, Kim, Glessner, Hou, Keating, Thomas, Garris, Deliard, Frackelton, Otieno, Chiavacci, Berkowitz, Hakonarson, Grant: "The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature." in: BMC medical genetics, Vol. 11, pp. 96, (2010) (PubMed).

You, Sun, Zhou, Sun, Liang, Zhai, Jiang: "PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4." in: Nature immunology, Vol. 10, Issue 12, pp. 1300-8, (2009) (PubMed).

Oshiumi, Matsumoto, Hatakeyama, Seya: "Riplet/RNF135, a RING finger protein, ubiquitinates RIG-I to promote interferon-beta induction during the early phase of viral infection." in: The Journal of biological chemistry, Vol. 284, Issue 2, pp. 807-17, (2009) (PubMed).

Target Details for RNF135

Target: RNF135 (Ring Finger Protein 135 (RNF135))

Alternative Name: RNF135

Background: The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene is located in a chromosomal region known to be frequently deleted in patients with neurofibromatosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq].

Molecular Weight: 47888

NCBI Accession: NP_001171921, NP_115698, NP_922921

UniProt: Q8IUD6