RNF135 antibody (Middle Region)

Catalog No. ABIN2775925

This Rabbit Polyclonal antibody specifically detects RNF135 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Guinea Pig and Horse.

Quick Overview for RNF135 antibody (Middle Region) (ABIN2775925)

Target: RNF135 (Ring Finger Protein 135 (RNF135))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF135 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RNF135 Antibody

Binding Specificity: Middle Region

Purpose: RNF135 Antibody - middle region

Sequence: DILHDLEEIQ EKLQESVTWK EAPEAQMQGE LLEAPSSSSC PLPDQSHPAL

Predicted Reactivity: Cow: 92%, Dog: 92%, Guinea Pig: 91%, Horse: 77%, Human: 100%, Mouse: 86%, Rat: 83%

Characteristics: This is a rabbit polyclonal antibody against RNF135. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RNF135

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8110815

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RNF135

Target: RNF135 (Ring Finger Protein 135 (RNF135))

Alternative Name: RNF135

Background:

Background Information: The protein encoded by RNF135 contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene is located in a chromosomal region known to be frequently deleted in patients with neurofibromatosis.

Gene Name: Ring finger protein 135

Alternative Symbols: L13, MMFD, REUL, Riplet

Protein Name: E3 ubiquitin-protein ligase RNF135

Molecular Weight: 48kDa

Gene ID: 84282

NCBI Accession: NP_115698

UniProt: Q8IUD6