Synaptojanin 2 antibody (AA 679-707)

Catalog No. ABIN1881861

Cited in 4+ publications. The Rabbit Polyclonal anti-Synaptojanin 2 antibody (Clone RB41921) (ABIN1881861) specifically detects Synaptojanin 2 in WB. The antibody is reactive with Human samples.

Quick Overview for Synaptojanin 2 antibody (AA 679-707) (ABIN1881861)

Target: Synaptojanin 2 (SYNJ2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Synaptojanin 2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB41921

Product Details anti-Synaptojanin 2 Antibody

Binding Specificity: AA 679-707

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SYNJ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 679-707 amino acids from the Central region of human SYNJ2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-Synaptojanin 2 antibody (ABIN1881861)

Ieguchi, Ueda, Kataoka, Satoh: "Role of the guanine nucleotide exchange factor Ost in negative regulation of receptor endocytosis by the small GTPase Rac1." in: The Journal of biological chemistry, Vol. 282, Issue 32, pp. 23296-305, (2007) (PubMed).

Rossi, Hawthorn, Platt, Burkhardt, Cowell, Ionov: "Identification of inactivating mutations in the JAK1, SYNJ2, and CLPTM1 genes in prostate cancer cells using inhibition of nonsense-mediated decay and microarray analysis." in: Cancer genetics and cytogenetics, Vol. 161, Issue 2, pp. 97-103, (2005) (PubMed).

Chuang, Tran, Rusk, Nakada, Berens, Symons: "Role of synaptojanin 2 in glioma cell migration and invasion." in: Cancer research, Vol. 64, Issue 22, pp. 8271-5, (2004) (PubMed).

Moghadaszadeh, Albrechtsen, Guo, Zaik, Kawaguchi, Borup, Kronqvist, Schroder, Davies, Voit, Nielsen, Engvall, Wewer: "Compensation for dystrophin-deficiency: ADAM12 overexpression in skeletal muscle results in increased alpha 7 integrin, utrophin and associated glycoproteins." in: Human molecular genetics, Vol. 12, Issue 19, pp. 2467-79, (2003) (PubMed).

Target Details for Synaptojanin 2

Target: Synaptojanin 2 (SYNJ2)

Alternative Name: SYNJ2

Background: The gene is a member of the inositol-polyphosphate 5-phosphatase family. The encoded protein interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis. Alternative splicing results in multiple transcript variants.

Molecular Weight: 165538

NCBI Accession: NP_003889

UniProt: O15056

Pathways: Inositol Metabolic Process