CACNA2D1 antibody (Internal Region)

Catalog No. ABIN190770

This anti-CACNA2D1 antibody is a Goat Polyclonal antibody detecting CACNA2D1 in ELISA and WB. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for CACNA2D1 antibody (Internal Region) (ABIN190770)

Target: CACNA2D1 (Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This CACNA2D1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Grade: Verified

Product Details anti-CACNA2D1 Antibody

Binding Specificity: Internal Region

Purpose: CACNA2D1

Sequence: QEIFNKYNKD KKVR

Cross-Reactivity: Human

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-QEIFNKYNKDKKVR, from the internal region of the protein sequence according to NP_000713.2.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 140 kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 123 kDa according to NP_000713.2). Recommended concentration: 0.03-0.1 μg/mL. Customer found it not suitable on Mouse and Rat protein.

Peptide ELISA: antibody detection limit dilution 1:16000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

References for anti-CACNA2D1 antibody (ABIN190770)

Neely, Hess, Costigan, Keene, Goulas, Langeslag, Griffin, Belfer, Dai, Smith, Diatchenko, Gupta, Xia, Amann, Kreitz, Heindl-Erdmann, Wolz, Ly, Arora, Sarangi, Dan, Novatchkova, Rosenzweig, Gibson et al.: "A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. ..." in: Cell, Vol. 143, Issue 4, pp. 628-38, (2010) (PubMed).

Target Details for CACNA2D1

Target: CACNA2D1 (Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1))

Alternative Name: CACNA2D1

Background: CACNA2D1, calcium channel, voltage-dependent, alpha 2/delta subunit 1, CACNA2, CACNL2A, CCHL2A, MHS3, H_DJ0560O14.1, WUGSC:H_DJ0560O14.1, calcium channel, L type, alpha 2 polypeptide, dihydropyridine-sensitive L-type, calcium channel alpha-2/delta subunit

Gene ID: 781, 12293, 25399

NCBI Accession: NP_000713