Transglutaminase 2, Tissue (TGM2) antibody

Antigen: Transglutaminase 2, Tissue (TGM2)

Synonyms: TG2, TGC, GNAH, G-ALPHA-h, TgaseII, TGM2, fc12b04, MGC136700, wu:fc12b04, zgc:136700, zgc:101081

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN190773

Additional Information

Alternative name: TGM2

Gene ID: 7052

Immunogen: C-NFESDKLKAVKGFR

Format: Affinity-purified

Description: All names and symbols: TGM2, transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase), TG2, TGC, C polypeptide, TGase C, TGase-H, protein-glutamine-gamma-glutamyltransferase, tissue transglutaminase, transglutaminase 2, transglutaminase C. Official Symbol: TGM2. RefSeq number(s): NP_004604.2

Specificity: This antibody is expected to recognise isoform a (NP_004604.2) only. Human

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:128,000. Western Blot: Approx 90kDa band observed in Human Lung lysates (calculated MW of 77.3kDa according to NP_004604.2). Recommended concentration: 0.03-0.1µg/ml.

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Restrictions: For Research Use only

Images

ABIN190773 (0.03 ug/ml) staining of Human Lung lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Publications

Publications: Verma, Wang, Manavathi et al.: "Increased expression of tissue transglutaminase in pancreatic ductal adenocarcinoma and its implications in drug resistance and metastasis." in: Cancer research, Vol. 66, Issue 21, pp. 10525-33, 2006 (PubMed).