Caspase 2 antibody

Catalog No. ABIN198455

The Rat Monoclonal anti-Caspase 2 antibody is suitable to detect Caspase 2 in samples from Human, Mouse, Rat, Dog and Monkey. It has been validated for WB and IP.

Quick Overview for Caspase 2 antibody (ABIN198455)

Target: Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))

Reactivity: Human, Mouse, Rat, Dog, Monkey

Host: Rat

Clonality: Monoclonal

Conjugate: This Caspase 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-Caspase 2 Antibody

Specificity: Recognizes an epitope in the human p19 subunit of, caspase-2. Detects bands of ~51kD (procaspase-2), ~32kD and ~18kD (cleavage products) by Western blot. Species cross-reactivity: mouse, rat, monkey, canine.

Purification: Protein G purified

Immunogen: His-tagged p19 fragment of recombinant human caspase-2.

Type of Immunogen: Recombinant protein

Isotype: IgG2a

Application Details

Application Notes: Approved: IP, WB (2 μg/mL)

Usage: Suitable for use in Immunoprecipitation and Western Blot. Western Blot: 2 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for Caspase 2

Target: Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))

Alternative Name: CASP2 / Caspase 2

Background: Name/Gene ID: CASP2
Subfamily: Cysteine C14
Family: Protease

Synonyms: CASP2, CASP-2, Caspase-2, PPP1R57, Protease ICH-1, NEDD-2, Caspase 2, ICH1, NEDD2

Gene ID: 835

UniProt: P42575

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Neurotrophin Signaling Pathway