Caspase 2 antibody (AA 198-226)

Catalog No. ABIN3030295

This Rabbit Polyclonal antibody specifically detects Caspase 2 in WB, ELISA, IHC and FACS. It exhibits reactivity toward Human.

Quick Overview for Caspase 2 antibody (AA 198-226) (ABIN3030295)

Target: Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-Caspase 2 Antibody

Binding Specificity: AA 198-226

Purification: Purified

Immunogen: A portion of amino acids 198-226 from the human protein was used as the immunogen for this Caspase-2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Caspase-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Caspase-2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for Caspase 2

Target: Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))

Alternative Name: Caspase-2

Background: CASP2 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. The protein exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of this protein is induced by a variety of apoptotic stimuli.

UniProt: P42575

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Neurotrophin Signaling Pathway